Pesquisa | BVS Violência e Saúde

1.

Acid Suspends the Circadian Clock in Hypoxia through Inhibition of mTOR.

Walton, Zandra E; Patel, Chirag H; Brooks, Rebekah C; Yu, Yongjun; Ibrahim-Hashim, Arig; Riddle, Malini; Porcu, Alessandra; Jiang, Tianying; Ecker, Brett L; Tameire, Feven; Koumenis, Constantinos; Weeraratna, Ashani T; Welsh, David K; Gillies, Robert; Alwine, James C; Zhang, Lin; Powell, Jonathan D; Dang, Chi V.

Cell ; 174(1): 72-87.e32, 2018 06 28.

Artigo em Inglês | MEDLINE | ID: mdl-29861175

2.

Sex, life, and death in MYC-driven lymphomagenesis.

Dang, Chi V.

Mol Cell ; 81(19): 3886-3887, 2021 10 07.

Artigo em Inglês | MEDLINE | ID: mdl-34624215

3.

MYC on the path to cancer.

Dang, Chi V.

Cell ; 149(1): 22-35, 2012 Mar 30.

Artigo em Inglês | MEDLINE | ID: mdl-22464321

4.

Control of T(H)17/T(reg) balance by hypoxia-inducible factor 1.

Dang, Eric V; Barbi, Joseph; Yang, Huang-Yu; Jinasena, Dilini; Yu, Hong; Zheng, Ying; Bordman, Zachary; Fu, Juan; Kim, Young; Yen, Hung-Rong; Luo, Weibo; Zeller, Karen; Shimoda, Larissa; Topalian, Suzanne L; Semenza, Gregg L; Dang, Chi V; Pardoll, Drew M; Pan, Fan.

Cell ; 146(5): 772-84, 2011 Sep 02.

Artigo em Inglês | MEDLINE | ID: mdl-21871655

5.

MYC disrupts transcriptional and metabolic circadian oscillations in cancer and promotes enhanced biosynthesis.

Cazarin, Juliana; DeRollo, Rachel E; Shahidan, Siti Noor Ain Binti Ahmad; Burchett, Jamison B; Mwangi, Daniel; Krishnaiah, Saikumari; Hsieh, Annie L; Walton, Zandra E; Brooks, Rebekah; Mello, Stephano S; Weljie, Aalim M; Dang, Chi V; Altman, Brian J.

PLoS Genet ; 19(8): e1010904, 2023 08.

Artigo em Inglês | MEDLINE | ID: mdl-37639465

6.

Epigenetic state determines inflammatory sensing in neuroblastoma.

Wolpaw, Adam J; Grossmann, Liron D; Dessau, Jessica L; Dong, May M; Aaron, Bailey J; Brafford, Patricia A; Volgina, Darya; Pascual-Pasto, Guillem; Rodriguez-Garcia, Alba; Uzun, Yasin; Arsenian-Henriksson, Marie; Powell, Daniel J; Bosse, Kristopher R; Kossenkov, Andrew; Tan, Kai; Hogarty, Michael D; Maris, John M; Dang, Chi V.

Proc Natl Acad Sci U S A ; 119(6)2022 02 08.

Artigo em Inglês | MEDLINE | ID: mdl-35121657

7.

mTOR Senses Intracellular pH through Lysosome Dispersion from RHEB.

Walton, Zandra E; Brooks, Rebekah C; Dang, Chi V.

Bioessays ; 41(7): e1800265, 2019 07.

Artigo em Inglês | MEDLINE | ID: mdl-31157925

8.

De novo synthesis of serine and glycine fuels purine nucleotide biosynthesis in human lung cancer tissues.

Fan, Teresa W M; Bruntz, Ronald C; Yang, Ye; Song, Huan; Chernyavskaya, Yelena; Deng, Pan; Zhang, Yan; Shah, Parag P; Beverly, Levi J; Qi, Zhen; Mahan, Angela L; Higashi, Richard M; Dang, Chi V; Lane, Andrew N.

J Biol Chem ; 294(36): 13464-13477, 2019 09 06.

Artigo em Inglês | MEDLINE | ID: mdl-31337706

9.

Myc-mediated transcriptional regulation of the mitochondrial chaperone TRAP1 controls primary and metastatic tumor growth.

Agarwal, Ekta; Altman, Brian J; Seo, Jae Ho; Ghosh, Jagadish C; Kossenkov, Andrew V; Tang, Hsin-Yao; Krishn, Shiv Ram; Languino, Lucia R; Gabrilovich, Dmitry I; Speicher, David W; Dang, Chi V; Altieri, Dario C.

J Biol Chem ; 294(27): 10407-10414, 2019 07 05.

Artigo em Inglês | MEDLINE | ID: mdl-31097545

10.

Links between metabolism and cancer.

Dang, Chi V.

Genes Dev ; 26(9): 877-90, 2012 May 01.

Artigo em Inglês | MEDLINE | ID: mdl-22549953

11.

Autophagy: clocking in for the night shift.

Brooks, Rebekah C; Dang, Chi V.

EMBO J ; 38(12)2019 06 17.

Artigo em Inglês | MEDLINE | ID: mdl-31133555

12.

Turning publicly available gene expression data into discoveries using gene set context analysis.

Ji, Zhicheng; Vokes, Steven A; Dang, Chi V; Ji, Hongkai.

Nucleic Acids Res ; 44(1): e8, 2016 Jan 08.

Artigo em Inglês | MEDLINE | ID: mdl-26350211

13.

MYC oncogene overexpression drives renal cell carcinoma in a mouse model through glutamine metabolism.

Shroff, Emelyn H; Eberlin, Livia S; Dang, Vanessa M; Gouw, Arvin M; Gabay, Meital; Adam, Stacey J; Bellovin, David I; Tran, Phuoc T; Philbrick, William M; Garcia-Ocana, Adolfo; Casey, Stephanie C; Li, Yulin; Dang, Chi V; Zare, Richard N; Felsher, Dean W.

Proc Natl Acad Sci U S A ; 112(21): 6539-44, 2015 May 26.

Artigo em Inglês | MEDLINE | ID: mdl-25964345

14.

MYC and metabolism on the path to cancer.

Hsieh, Annie L; Walton, Zandra E; Altman, Brian J; Stine, Zachary E; Dang, Chi V.

Semin Cell Dev Biol ; 43: 11-21, 2015 Jul.

Artigo em Inglês | MEDLINE | ID: mdl-26277543

15.

Tumorigenicity of hypoxic respiring cancer cells revealed by a hypoxia-cell cycle dual reporter.

Le, Anne; Stine, Zachary E; Nguyen, Christopher; Afzal, Junaid; Sun, Peng; Hamaker, Max; Siegel, Nicholas M; Gouw, Arvin M; Kang, Byung-Hak; Yu, Shu-Han; Cochran, Rory L; Sailor, Kurt A; Song, Hongjun; Dang, Chi V.

Proc Natl Acad Sci U S A ; 111(34): 12486-91, 2014 Aug 26.

Artigo em Inglês | MEDLINE | ID: mdl-25114222

16.

c-MYC mRNA tail tale about glutamine control of transcription.

Dang, Chi V.

EMBO J ; 36(13): 1806-1808, 2017 07 03.

Artigo em Inglês | MEDLINE | ID: mdl-28507224

17.

MYC, Metabolic Synthetic Lethality, and Cancer.

Hsieh, Annie L; Dang, Chi V.

Recent Results Cancer Res ; 207: 73-91, 2016.

Artigo em Inglês | MEDLINE | ID: mdl-27557535

18.

Stress eating and tuning out: cancer cells re-wire metabolism to counter stress.

Stine, Zachary E; Dang, Chi V.

Crit Rev Biochem Mol Biol ; 48(6): 609-19, 2013.

Artigo em Inglês | MEDLINE | ID: mdl-24099138

19.

HIF-1 inhibits mitochondrial biogenesis and cellular respiration in VHL-deficient renal cell carcinoma by repression of C-MYC activity.

Zhang, Huafeng; Gao, Ping; Fukuda, Ryo; Kumar, Ganesh; Krishnamachary, Balaji; Zeller, Karen I; Dang, Chi V; Semenza, Gregg L.

Cancer Cell ; 11(5): 407-20, 2007 May.

Artigo em Inglês | MEDLINE | ID: mdl-17482131

20.

HIF-dependent antitumorigenic effect of antioxidants in vivo.

Gao, Ping; Zhang, Huafeng; Dinavahi, Ramani; Li, Feng; Xiang, Yan; Raman, Venu; Bhujwalla, Zaver M; Felsher, Dean W; Cheng, Linzhao; Pevsner, Jonathan; Lee, Linda A; Semenza, Gregg L; Dang, Chi V.

Cancer Cell ; 12(3): 230-8, 2007 Sep.

Artigo em Inglês | MEDLINE | ID: mdl-17785204

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Acid Suspends the Circadian Clock in Hypoxia through Inhibition of mTOR.

Sex, life, and death in MYC-driven lymphomagenesis.

MYC on the path to cancer.

Control of T(H)17/T(reg) balance by hypoxia-inducible factor 1.

MYC disrupts transcriptional and metabolic circadian oscillations in cancer and promotes enhanced biosynthesis.

Epigenetic state determines inflammatory sensing in neuroblastoma.

mTOR Senses Intracellular pH through Lysosome Dispersion from RHEB.

De novo synthesis of serine and glycine fuels purine nucleotide biosynthesis in human lung cancer tissues.

Myc-mediated transcriptional regulation of the mitochondrial chaperone TRAP1 controls primary and metastatic tumor growth.

Links between metabolism and cancer.

Autophagy: clocking in for the night shift.

Turning publicly available gene expression data into discoveries using gene set context analysis.

MYC oncogene overexpression drives renal cell carcinoma in a mouse model through glutamine metabolism.

MYC and metabolism on the path to cancer.

Tumorigenicity of hypoxic respiring cancer cells revealed by a hypoxia-cell cycle dual reporter.

c-MYC mRNA tail tale about glutamine control of transcription.

MYC, Metabolic Synthetic Lethality, and Cancer.

Stress eating and tuning out: cancer cells re-wire metabolism to counter stress.

HIF-1 inhibits mitochondrial biogenesis and cellular respiration in VHL-deficient renal cell carcinoma by repression of C-MYC activity.

HIF-dependent antitumorigenic effect of antioxidants in vivo.